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Search Results for " epothilone a "

9

Compounds

Cat No. Product Name Synonyms Targets
T6490 Epothilone A epothile,Epo A Apoptosis , Microtubule Associated
Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.
T6075 Epothilone B Patupilone,EPO 906 Apoptosis , Microtubule Associated , Antibiotic , Antifungal
Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, patupilone induces microtubule polymerization and stabilizes microtubules against depolymerization conditi...
T31657 Epothilone F
Epothilone F is a derivative or analogue of Epothilone D. Epothilone F is also an active metabolite of Epothilone D. In molecule of Epothilone F, a hydroxymethyl group is on the thiazole ring. Like taxanes, Epothilone F ...
T82453 Epothilone D1
Epothilone D1, a naturally derived isolate, exhibits cytotoxic effects on mouse fibroblasts.
T72934 Epothilone E
Epothilone E, a derivative of epothilone, functions by inhibiting microtubule protein activity, thereby halting cell division and exhibiting anti-tumor capabilities.
T68232 Epofolate
Epofolate is folate receptor-targeting antimitotic agent with potential antineoplastic activity. Folate receptor-targeted epothilone BMS753493 contains an epothilone moiety linked to a single folate molecule. Mediated th...
T71577 KOS-1584
KOS-1584 is a second-generation epothilone with potential antineoplastic activity. Epothilone KOS-1584 binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization, which m...
T69480 Sagopilone
Sagopilone is a fully synthetic low-molecular-weight epothilone with potential antineoplastic activity. Sagopilone binds to tubulin and induces microtubule polymerization while stabilizing microtubules against depolymeri...
T68860 Iso-Fludelone
Iso-Fludelone is the third-generation epothilone B analogue with potential anti-mitotic and antineoplastic activites. Iso-fludelone binds to tubulin and induces microtubule polymerization and stabilizes microtubules agai...
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