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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6490 | Epothilone A | epothile,Epo A | Apoptosis , Microtubule Associated |
Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM. | |||
T6075 | Epothilone B | Patupilone,EPO 906 | Apoptosis , Microtubule Associated , Antibiotic , Antifungal |
Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, patupilone induces microtubule polymerization and stabilizes microtubules against depolymerization conditi... | |||
T31657 | Epothilone F | ||
Epothilone F is a derivative or analogue of Epothilone D. Epothilone F is also an active metabolite of Epothilone D. In molecule of Epothilone F, a hydroxymethyl group is on the thiazole ring. Like taxanes, Epothilone F ... | |||
T82453 | Epothilone D1 | ||
Epothilone D1, a naturally derived isolate, exhibits cytotoxic effects on mouse fibroblasts. | |||
T72934 | Epothilone E | ||
Epothilone E, a derivative of epothilone, functions by inhibiting microtubule protein activity, thereby halting cell division and exhibiting anti-tumor capabilities. | |||
T68232 | Epofolate | ||
Epofolate is folate receptor-targeting antimitotic agent with potential antineoplastic activity. Folate receptor-targeted epothilone BMS753493 contains an epothilone moiety linked to a single folate molecule. Mediated th... | |||
T71577 | KOS-1584 | ||
KOS-1584 is a second-generation epothilone with potential antineoplastic activity. Epothilone KOS-1584 binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization, which m... | |||
T69480 | Sagopilone | ||
Sagopilone is a fully synthetic low-molecular-weight epothilone with potential antineoplastic activity. Sagopilone binds to tubulin and induces microtubule polymerization while stabilizing microtubules against depolymeri... | |||
T68860 | Iso-Fludelone | ||
Iso-Fludelone is the third-generation epothilone B analogue with potential anti-mitotic and antineoplastic activites. Iso-fludelone binds to tubulin and induces microtubule polymerization and stabilizes microtubules agai... |